Autophagy is a stress response process where protein aggregates and damaged organelles are degraded via delivery to lysosomes. The dysregulation of this proteostatic process increases with age which ultimately leads to disruption of cellular homeostasis.

I am interested in understanding the role of autophagy in germline stem cell (GSC) aging and how it is regulated in Drosophila ovary.

• Nilangekar, K., Murmu, N., Sahu, G. and Shravage, B.V., 2019. Generation and characterization of germline-specific autophagy and mitochondrial reactive oxygen species reporters in Drosophila. Frontiers in cell and developmental biology, 7, p.47.